| Bioactivity | KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers[1]. |
| Name | KRAS G12C inhibitor 61 |
| CAS | 2300967-40-0 |
| Formula | C31H33ClFN7O2 |
| Molar Mass | 590.09 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brian Alan Lanman, et al. Inhibitors of kras g12c and methods of using the same. Patent. WO2019051291. |