Bioactivity | KR-27370 (compound 7f) is an antiviral agent and selective PI4KIIIβ/PI4KIIIα inhibitor (IC50: 3.1 nM/15.8 nM), against hRV, Ke Saatchivirus and other enteroviruses have inhibitory activity[1].br/[1]. |
Invitro | KR-27370 的细胞毒性低 (CC50: >100 μM, H1HeLa),对 hRV B14,hRV A16,hRV A21 的 EC50 分别为 22 nM,32 nM,36 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> KR-27370 相关抗体: |
Formula | C27H27N3O6S2 |
Molar Mass | 553.65 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. G Vishakantegowda A, et al. Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents. RSC Med Chem. 2023 Dec 21;15(2):704-719. |