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KIO-301 chloride

CAS: 1643463-59-5 F: C29H38ClN5O W: 508.10

KIO-301 chloride is an azobenzene photoswitch compound that can block voltage-gated ion channels, including hyperpolaris
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Bioactivity KIO-301 chloride is an azobenzene photoswitch compound that can block voltage-gated ion channels, including hyperpolarisation-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium channels during exposure to visible light[1].
Name KIO-301 chloride
CAS 1643463-59-5
Formula C29H38ClN5O
Molar Mass 508.10
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Eric Daniels, et al. An Intravitreal 'Photoswitch' Molecule (KIO-301) for Reanimation in Retinitis Pigmentosa: a first-in-human trial. Investigative Ophthalmology & Visual Science June 2023, Vol.64, 5444.