Bioactivity | KF15766 (compd 34E) is an orally active TXA2 and H1 dual antagonist with Kis of 740 and 20 nM. KF15766 can be used for antiallergic research[1]. |
In Vivo | KF15766 (0.3, 10 mg/kg, p.o.) 预防组胺和 U-46619 诱导的豚鼠支气管收缩[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 124907-44-4 |
Formula | C30H31NO3.1/2C4H4O4 |
Molar Mass | 511.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ohshima E, et al. Dibenz[b,e]oxepin derivatives: novel antiallergic agents possessing thromboxane A2 and histamine H1 dual antagonizing activity. 1. J Med Chem. 1993 Feb 5;36(3):417-20. |