| Bioactivity | KDM1/CDK1-IN-1 (compound 4) is a potent KDM1 and CDK1 inhibitor, with IC50 values of 0.096 and 0.078 μM, respectively.KDM1/CDK1-IN-1 induces cell cycle arrest at G2/M phase and apoptosis in HOP-92 cells. KDM1/CDK1-IN-1 exhibits potent cytotoxic activity against the CCRF-CEM, HOP-92 and Hep-G2 cells, with IC50 values of 16.34, 3.45 and 7.79 μM, respectively[1]. |
| Invitro | KDM1/CDK1-IN-1 (compound 4) induces apoptosis by the activation of Caspase-3[1]. |
| Name | KDM1/CDK1-IN-1 |
| Formula | C22H17N5O3S |
| Molar Mass | 431.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |