Janelia Fluor® 646, SE_product_DataBase

Bioactivity	Janelia Fluor? 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging[1]. Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Storage: protect from light.
Invitro	Excitation maximum=646 nm; emission maximum=664 nm[1].JF646 can serve as ligand for self-labeling tag (such as HaloTag)[1].Janelia Fluor® 646, SE (JF646, SE) is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2].
Name	Janelia Fluor® 646, SE
CAS	1811539-59-9
Formula	C33H31N3O6Si
Molar Mass	593.70
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Grimm JB, et al. A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat Methods. 2015;12(3):244-250. doi:10.1038/nmeth.3256 [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.

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