Bioactivity | HKSOX-1m (5/6-mixture) is a O2•− fluorescent probe for mitochondria-targeting (Ex/Em=509/534nm; green), exhibiting excellent selectivity and sensitivity toward O2•− over a broad range of pH, strong oxidants, and abundant reductants found in cells[1]. |
Invitro | HKSOX-1m (5/6-mixture) (10 μM) 能够灵敏地在非常低的激光功率输出条件下,捕获分化的人 THP-1 细胞的基础信号,和受 Antimycin A (1 μM) 刺激的线粒体 O2•− 的信号 (蔡司 LSM 510 Meta 的 514 nm 激发波长的强度为 1%)[1]。 |
Name | HKSOX-1m (5/6-mixture) |
CAS | 1786411-19-5 |
Formula | C49H37Cl2F10N2O10PS2 |
Molar Mass | 1169.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Jun Jacob Hu, et al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc . 2015 Jun 3;137(21):6837-43. |