Janelia Fluor® 646, Azide_product_DataBase

Bioactivity	Janelia Fluor? 646, Azide (JF646, Azide) is a red fluorogenic fluorescent dye containing a click chemistry group Azide. Janelia Fluor? 646, Azide can be used for live-cell imaging experiments[1][2]. Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Storage: protect from light.
Invitro	Maximum absorption wavelength (λabs)= 646 nm, maximum emission wavelength (λem)=664 nm[1].JF646 can serve as a ligand for self-labeling tag (such as HaloTag)[1].Janelia Fluor® 646, Azide is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2].
Name	Janelia Fluor® 646, Azide
Formula	C37H44N6O6Si
Molar Mass	696.87
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Grimm JB, Muthusamy AK, Liang Y, et al. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nat Methods. 2017;14(10):987-994. doi:10.1038/nmeth.4403. [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.

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