Janelia Fluor® 646, Tetrazine_product_DataBase

Bioactivity	Janelia Fluor? 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging[1]. Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Storage: protect from light.
Invitro	Excitation maximum=646 nm; emission maximum=664 nm[1].JF646 can serve as ligand for self-labeling tag (such as HaloTag) [1].JF646, Tetrazine is modified by JF646. JF646, a red fluorescent dye, is photostable, membrane-permeable, has a high extinction coefficient[2]
Name	Janelia Fluor® 646, Tetrazine
CAS	2042192-00-5
Formula	C38H35N7O3Si
Molar Mass	665.82
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Grimm JB, et al. A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat Methods. 2015;12(3):244-250. doi:10.1038/nmeth.3256 [2]. Basu S, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nat Commun. 2018;9(1):2520. Published 2018 Jun 28.

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