Bioactivity | JYL 1511 is a partial agonist of vanilloid receptor VR1[1]. |
Invitro | JYL 1511 抑制 [3H]Resiniferatoxin 与大鼠 VR1 的结合,Ki 为 50.4 nM[1]。JYL 1511 抑制过表达大鼠 VR1 的 CHO 细胞中辣椒素诱导的 45Ca2+ 摄取 (IC50: 3.4 nM)[1]. |
Name | JYL 1511 |
CAS | 623166-14-3 |
Formula | C21H29N3O3S2 |
Molar Mass | 435.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang Y, et al. High-affinity partial agonists of the vanilloid receptor. Mol Pharmacol. 2003 Aug;64(2):325-33. |