Bioactivity | JW 618 is a selective ABHD6 inhibitor, with IC50s of 38 and 13 nM for mouse and rat ABHD6[1]. |
Invitro | JW 618 (0.1-50 μM,30 分钟) 抑制小鼠或大鼠脑蛋白质组中 MAGL 和 ABHD6 的蛋白表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> JW 618 相关抗体: |
CAS | 1416133-88-4 |
Formula | C17H14F6N2O2 |
Molar Mass | 392.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chang JW, et al. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol. 2012 May 25;19(5):579-88. |