| Bioactivity | JNJ-40413269 is an inhibitor for FAAH, that inhibits human FAAH and rats FAAH with IC50 of 28 nM and 270 nM. JNJ-40413269 exhibits analgesic efficacy in rat spinal nerve ligation model and exhibits good pharmacokinetic characteristics in rats[1]. |
| Target | IC50: 28 nM (hFAAH), 270 nM (rFAAH) |
| CAS | 1184847-16-2 |
| Formula | C19H15ClF3N3O |
| Molar Mass | 393.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Keith JM, et al., 1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1280-4. |
JNJ-40413269
CAS: 1184847-16-2 F: C19H15ClF3N3O W: 393.79
JNJ-40413269 is an inhibitor for FAAH, that inhibits human FAAH and rats FAAH with IC50 of 28 nM and 270 nM. JNJ-4041326
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