| Bioactivity | JKC363, a selective melanocortin MC4 receptor antagonist, has a 90-fold higher affinity at the MC4 receptor (IC50=0.5 nM) than at the MC3 receptor (44.9 nM). JKC-363 blocks the stimulatory effect of α-MSH on TRH release. Anti-hyperalgesic effect[1][2]. |
| Name | JKC363 |
| CAS | 436083-30-6 |
| Shortening | {Mpa}-EH-{D-2-Nal}-RWGCPPKD (Disulfide bridge:Mpa1-Cys8) |
| Formula | C69H91N19O16S2 |
| Molar Mass | 1506.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
JKC363
CAS: 436083-30-6 F: C69H91N19O16S2 W: 1506.71
JKC363, a selective melanocortin MC4 receptor antagonist, has a 90-fold higher affinity at the MC4 receptor (IC50=0.5 nM
Data collection：peptidedb@qq.com
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