| Bioactivity | JAK1/TYK2-IN-4 is a dual inhibitor of JAK and TYK2, with IC50s of 39 nM and 21 nM, respectively. JAK1/TYK2-IN-4 has oral bioavailability[1]. |
| Name | JAK1/TYK2-IN-4 |
| CAS | 2734918-33-1 |
| Formula | C17H23N7O |
| Molar Mass | 341.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xue Cui, et al. Therapeutic potential of a synthetic dual JAK1/TYK2 inhibitor in inflammatory bowel disease. Int Immunopharmacol. 2023 Nov 20:126:111238. |
JAK1/TYK2-IN-4
CAS: 2734918-33-1 F: C17H23N7O W: 341.41
JAK1/TYK2-IN-4 is a dual inhibitor of JAK and TYK2, with IC50s of 39 nM and 21 nM, respectively. JAK1/TYK2-IN-4 has oral
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