| Bioactivity | JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits IFN-α2B-induced phosphorylation of STAT3 in Jurkat cells (IC50=17.2 nM)[1]. |
| Name | JAK-IN-26 |
| CAS | 2417134-93-9 |
| Formula | C22H24N6O3 |
| Molar Mass | 420.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou M, et al. Pyridine derivatives as TYK2 kinase inhibitors and preparation thereof. China, CN113563309 A 2021-10-29. |
JAK-IN-26
CAS: 2417134-93-9 F: C22H24N6O3 W: 420.46
JAK-IN-26 (compound 2) is an orally active JAK inhibitor with good pharmacokinetic characteristics. JAK-IN-26 inhibits I
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