Bioactivity | Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities. Anticancer agent 118 shows high activity against Gram-positive strains and antiproliferative activities against prostate PC3 cells. Anticancer agent 118 can be used for antitumor research[1]. |
Invitro | Anticancer agent 118 (Compound 3) (0-100 μM;72 小时) 显示对前列腺癌 PC3 细胞的高度抗增殖活性,以及诱导 PC3 细胞凋亡/坏死[1]。 Cell Proliferation Assay[1] Cell Line: |
Name | Anticancer agent 118 |
CAS | 864443-43-6 |
Formula | C19H19ClFN3O4 |
Molar Mass | 407.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Struga M, et.al. N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents. ACS Omega. 2023 May 18;8(21):18663-18684. |