| Bioactivity | J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases[1]. |
| Name | J5 peptide |
| CAS | 444305-16-2 |
| Sequence | Glu-Lys-Pro-Lys-Val-Glu-Ala-Tyr-Lys-Ala-Ala-Ala-Ala-Pro-Ala |
| Shortening | EKPKVEAYKAAAAPA |
| Formula | C70H114N18O21 |
| Molar Mass | 1543.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Smith CE, et al. Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9595-600. |
J5 peptide
CAS: 444305-16-2 F: C70H114N18O21 W: 1543.76
J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.