| Bioactivity | Ir-ImNO is a mitochondria-targeted two-photon probe with excellent cell membrane permeability, capable of detecting both endogenous and exogenous cell membrane permeability. Ir-ImNO can monitor different immune response states of macrophages through various imaging techniques, including one-photon and two-photon phosphorescence imaging as well as phosphorescence lifetime imaging. Ir-ImNO can be utilized in the research to assist in the clinical monitoring of immunotherapy[1]. |
| Invitro | Ir-ImNO (5 μM; 6-48 h) 在 4T1 和 RAW 264.7 细胞中的细胞毒性较低，细胞孵育 48 h后，细胞存活率仍在 80%以上[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Ir-ImNO 相关抗体: |
| Formula | C49H36ClIrN6 |
| Molar Mass | 936.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wen Y, et al. A Mitochondria-Targeted Nitric Oxide Probe for Multimodality Imaging of Macrophage Immune Responses. Anal Chem. 2024;96(17):6666-6673. |