| Bioactivity | InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM[1]. |
| Target | IC50: 17.7 μM (InhA) |
| Invitro | InhA-IN-3 (Compound TU12) shows antitubercular activity with a MIC of 0.78±0.59 µg/mL against Mycobacterium tuberculosis[1]. |
| Name | InhA-IN-3 |
| CAS | 900701-83-9 |
| Formula | C14H12ClN3O2S |
| Molar Mass | 321.78 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Doğan ŞD, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402. |