| Bioactivity | Antibacterial agent 58, an antibacterial agent, significantly lowers MIC value of antibacterial agent Ceftazidime[1]. |
| Invitro | Antibacterial agent 58 (example 23) significantly lowers MIC value of Ceftazidime (MIC=1, 2, 8 mcg/ml for E. coli NCTC 1335 1, E. coli M50, and E. coli 7MP, respectively). Antibacterial agent 58 significantly lowers MIC values of the antibacterial agent Ceftazidime (MIC=0.2~2 mcg/ml for class A ESBL; 2-8 mcg/ml for class C ESBL; 4-8 mcg/ml for KPC ESBL)[1]. From WO2013030735A1, example 23.Class A ESBL: E.coli W 13353; E.coli W3351; E.coli W 13352Class C ESBL: E.coli M 50; E.coli 7 MIP; E.coli B 89KPC ESBL: K.pneumoniae H 520; K.pneumoniae H 521; K. pneumoniae H 522Class D ESBL: A.Baumannii13301; A.baumannii 13304 |
| Name | Antibacterial agent 58 |
| CAS | 1426572-65-7 |
| Formula | C8H11N6NaO5S |
| Molar Mass | 326.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sachin Bhagwat, et al. 1,6- diazabicyclo [3,2,1] octan- 7 - one derivatives and their use in the treatment of bacterial infections. |