| Bioactivity | IRE1α kinase-IN-9 (compound 2) is a potent IRE-1α inhibitor，exhibits an average IC50 value of <0.1 μM. IRE1α kinase-IN-9 can be used for research in diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD)[1]. |
| Target | IC50: <0.1 μM (IRE1α) |
| Name | IRE1α kinase-IN-9 |
| CAS | 1338933-30-4 |
| Formula | C24H24N2O6 |
| Molar Mass | 436.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zeng Q, et al. Benzoheterocyclecarboxaldehyde derivatives as IRE-1α inhibitors and their preparation and use for the treatment of diseases. World Intellectual Property Organization, WO2011127070 A2. 2011-10-13. |