| Bioactivity | IRE1α kinase-IN-3 (compound 2) is a potent IRE1α inhibitor with an Ki of 480 nM. IRE1α kinase-IN-3 is the ATP-competitive ligands of IRE1α[1]. |
| Target | Ki: 480 nM (IRE1α) |
| Name | IRE1α kinase-IN-3 |
| CAS | 2416223-41-9 |
| Formula | C29H32N6O3S |
| Molar Mass | 544.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feldman HC, et al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156. |
IRE1α kinase-IN-3
CAS: 2416223-41-9 F: C29H32N6O3S W: 544.67
IRE1α kinase-IN-3 (compound 2) is a potent IRE1α inhibitor with an Ki of 480 nM. IRE1α kinase-IN-3 is the ATP-competi
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