| Bioactivity | IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1]. |
| Name | IRAK4-IN-10 |
| CAS | 2681278-09-9 |
| Formula | C22H24N8 |
| Molar Mass | 400.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13(3):336-337. |
IRAK4-IN-10
CAS: 2681278-09-9 F: C22H24N8 W: 400.48
IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signali
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