| Bioactivity | IMTPPE is an inhibitor of the androgen receptor (AR) in C4-2 prostate cancer cells, inhibiting its transcriptional activity and protein levels. IMTPPE inhibited the proliferation of AR-positive prostate cancer cells but had no effect on AR-negative prostate cancer cells. IMTPPE also inhibited the growth of enzalutamide-resistant 22Rv1 xenograft tumors[1]. |
| CAS | 851688-13-6 |
| Formula | C20H27N3O2S |
| Molar Mass | 373.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Inhibition of androgen receptor function and level in castration-resistant prostate cancer cells by 2-((isoxazol-4-ylmethyl)thio)-1-(4-phenylpiperazin-1- yl)ethanone |