| Bioactivity | CK0683A is a novel biaminourea antibiotic with antiplaque effects and demonstrated efficacy in experimental mouse dental disease models. A 12-week study in beagles compared its efficacy in terms of plaque and gingivitis reduction, staining potential, and safety. Dogs were selected as the study subjects because the onset and progression of canine periodontal disease is similar to that of humans. As a positive control for plaque and gingivitis reduction and staining, chlorhexidine acetate was selected because it is effective in both humans and dogs. |
| CAS | 83539-21-3 |
| Formula | C32H57N9O5S |
| Molar Mass | 679.92 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Basic Biological Sciences: Effects of Chlorhexidine and Four Antimicrobial Compounds on Plaque, Gingivitis, and Staining in Beagle Dogs |