Bioactivity | IIQLPEIVVV TFA is a specific inhibitor of Drp1-Mff interaction. IIQLPEIVVV TFA can distinguish physiological from pathological fission and block physiological fission, thus leading to mitochondrial dysfunction. IIQLPEIVVV TFA can be used in the study of Huntington's disease[1]. | ||||||
Sequence | Ile-Ile-Gln-Leu-Pro-Glu-Ile-Val-Val-Val | ||||||
Shortening | IIQLPEIVVV | ||||||
Formula | C54H95N11O14.xC2HF3O2 | ||||||
Molar Mass | 1122.40 (free base) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Reference | [1]. Kornfeld O S, et al. Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo[J]. Scientific reports, 2018, 8(1): 14034. |