| Bioactivity | IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC50 of 42 nM and 109 nM, for MST1 and MST2. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 ameliorates diabetes in Streptozotocin (HY-13753)-induced type 1 diabetes (T1D) mouse models[1]. |
| Target | IC50: 42 nM (MST1); 109 nM (MST2) |
| CAS | 2414484-01-6 |
| Formula | C20H18F2N6O3S |
| Molar Mass | 460.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
IHMT-MST1-39
CAS: 2414484-01-6 F: C20H18F2N6O3S W: 460.46
IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC50 of 42 nM and 109 nM, for MST1 and MST2. IHMT-MST1-3
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