IFN-γ Antagonist 1_product_DataBase

Bioactivity	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation[1].
Name	IFN-γ Antagonist 1
CAS	158040-83-6
Sequence	Ala-Tyr-{Cys(Acm)}-Arg-Asp-Gly-Lys-Ile-Gly-Pro-Pro-Lys-Leu-{α-Asp}-Ile-Arg-Lys-{α-Glu}-{α-Glu}-Lys-Gln-Ile
Shortening	AY-{C<Acm>}-RDGKIGPPKL-{α-D}-IRK-{α-E}-{α-E}-KQI
Formula	C115H194N34O34S
Molar Mass	2629.04
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Seelig GF, et al. Development of a receptor peptide antagonist to human gamma-interferon and characterization of its ligand-bound conformation using transferred nuclear Overhauser effect spectroscopy. J Biol Chem. 1995 Apr 21;270(16):9241-9.

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