| Bioactivity | Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies[1]. |
| In Vivo | Dexchlorpheniramine (2-10 mg/kg; IP, single dosage) and Ranitidine (10-50 mg/kg) co-administration can simultaneous blockade of H1 and H2 receptors, and protects both the cortical plate and the white matter against the excitotoxic challenge in Swiss pups pretreated with IL-9[1]. |
| Name | Dexchlorpheniramine |
| CAS | 25523-97-1 |
| Formula | C16H19ClN2 |
| Molar Mass | 274.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Patkai J, et al. Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatr Res. 2001 Aug;50(2):222-30. |
Dexchlorpheniramine
CAS: 25523-97-1 F: C16H19ClN2 W: 274.79
Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with antic
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