| Bioactivity | IDOR-4 is a type IV CFTR corrector. IDOR-4 restores F508del-CFTR trafficking to the cell surface[1]. |
| Invitro | IDOR-4 (0.1-1000 nM，24 小时) 恢复 F508del-CFTR 功能 (YFP 淬灭测定)，CFBE 细胞中 F508del-CFTR C 带表达增加表明，反映了向细胞表面的运输[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> IDOR-4 相关抗体: |
| CAS | 2839901-24-3 |
| Formula | C44H51F3N12O7 |
| Molar Mass | 916.95 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Marchesin V, et al. A uniquely efficacious type of CFTR corrector with complementary mode of action. Sci Adv. 2024 Mar;10(9):eadk1814. |