| Bioactivity | I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC)[1][2]. |
| Name | I-SAP |
| CAS | 133538-58-6 |
| Formula | C22H30INO4S |
| Molar Mass | 531.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Saussy DL Jr, et al. Binding of a novel radioiodinated thromboxane A2/prostaglandin H2 antagonist to guinea pig lung membranes. Eicosanoids. 1992;5(1):1-4. [2]. Schrör K, et al. Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine. Biochem Pharmacol. 1995 Mar 30;49(7):921-7. |