| Bioactivity | Hit 1 is an activator of ansulin degrading enzyme (IDE), with an EC50 of 5.5 μM. Hit 1 can decrease glucose-stimulating insulin secretion[1]. |
| Target | EC50: 5.5 μM (ansulin degrading enzyme) |
| Name | Hit 1 |
| CAS | 2785377-42-4 |
| Formula | C22H24N4O3S2 |
| Molar Mass | 456.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kraupner N, et, al. Identification of indole-based activators of insulin degrading enzyme. Eur J Med Chem. 2022 Jan 15;228:113982. |