| Bioactivity | Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist, with mixed competitive and noncompetitive activity. Hexamethonium Bromide has anti-hypertensive activity. Hexamethonium Bromide attenuates sympathetic activity and blood pressure in spontaneously hypertensive animal models[1][2][3][4]. |
| Invitro | Hexamethonium Bromide (100 µM; 60 minutes) abolishes epibatidine-induced depolarisations of smooth muscle cells[1].The α3β4α5 receptors have greater sensitivity to Hexamethonium Bromide than the other potential ganglionic models, α3β4, α3β2, and α3β2α5[2]. |
| Name | Hexamethonium Bromide |
| CAS | 55-97-0 |
| Formula | C12H30Br2N2 |
| Molar Mass | 362.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Hexamethonium Bromide
CAS: 55-97-0 F: C12H30Br2N2 W: 362.19
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist, with mixed competi
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