| Bioactivity | Etidronic acid (Etidronate) is an orally and intravenously active bisphosphonate. Etidronic acid inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid has anticancer activity. Etidronic acid is a chelating agent and can be used to remove heavy metal in water[1][2][3][4]. | ||||||||||||
| Invitro | Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells[3].Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy[5]. | ||||||||||||
| Name | Etidronic acid | ||||||||||||
| CAS | 2809-21-4 | ||||||||||||
| Formula | C2H8O7P2 | ||||||||||||
| Molar Mass | 206.03 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Etidronic acid
CAS: 2809-21-4 F: C2H8O7P2 W: 206.03
Etidronic acid (Etidronate) is an orally and intravenously active bisphosphonate. Etidronic acid inhibits resorption of
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