| Bioactivity | Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo[1][2][3]. |
| Invitro | Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic[1]. |
| Name | Hexa-D-arginine TFA |
| CAS | 958204-56-3 |
| Sequence | Arg-Arg-Arg-Arg-Arg-Arg-NH2 |
| Shortening | RRRRRR-NH2 |
| Formula | C38H76F3N25O8 |
| Molar Mass | 1068.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |