PeptideDB

Hexa-D-arginine TFA

CAS: 958204-56-3 F: C38H76F3N25O8 W: 1068.17

Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for
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Bioactivity Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo[1][2][3].
Invitro Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic[1].
Name Hexa-D-arginine TFA
CAS 958204-56-3
Sequence Arg-Arg-Arg-Arg-Arg-Arg-NH2
Shortening RRRRRR-NH2
Formula C38H76F3N25O8
Molar Mass 1068.17
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.