| Bioactivity | Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light[1][2][3]. |
| Invitro | Hematoporphyrin (20-120 nM; 60 min) dose-dependently inhibits cell viability in U87 and U251 glioma cells, with IC50s of 85 and 166 nM, respectively[2].Hematoporphyrin (85 nM; 60 min) induces cell apoptosis via induction of ROS in U87 cells[2].Hematoporphyrin (85 nM; 60 min) induces morphological changes of U87 cells under the red light, including shrinking, fragmentation[2]. Cell Viability Assay[2] Cell Line: |
| Name | Hematoporphyrin |
| CAS | 14459-29-1 |
| Formula | C34H38N4O6 |
| Molar Mass | 598.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 |
Hematoporphyrin
CAS: 14459-29-1 F: C34H38N4O6 W: 598.69
Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding prot
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