| Bioactivity | Hematein is a oxidation product of hematoxylin acted as a dye[1]. Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells[2]. | ||||||||||||
| Invitro | Hematein (10-100 μM; 14 days) inhibits cells growth in A427 lung cancer cells[1]. Hematein (50 and 100 μM; 48 hours) induces apoptosis in A427 lung cancer cells[1]. Hematein (50 and 100 μM; 48 hours) inhibits CK2-specific Akt phosphorylation[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | Hematein | ||||||||||||
| CAS | 475-25-2 | ||||||||||||
| Formula | C16H12O6 | ||||||||||||
| Molar Mass | 300.26 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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