| Bioactivity | HU-308 is a highly selective CB2 receptor agonist belonging to the synthetic cannabinoid analogues. The affinity of HU-308 to CB2 receptor is more than 440 times higher than that of CB1 receptor. CB2 receptors are mainly distributed in immune cells and are responsible for regulating the immunosuppressive effects of the endocannabinoid system (ECS). HU-308 has anti-inflammatory, neuroprotective and bioactive properties that regulate microglia function. HU-308 can be used in the study of neuroinflammation and retinal diseases[1]. |
| CAS | 1432056-41-1 |
| Formula | C27H42O3 |
| Molar Mass | 414.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Young A P, et al. Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro[J]. ACS Pharmacology & Translational Science, 2024. |