| Bioactivity | HSR-IN-1 (Compound 28) is an effective hSR (human serine racemase) inhibitor. In the presence of the cofactor Pyridoxal 5'-phosphate monohydrate (HY-W011727A), HSR-IN-1 has a Kd value of 5.4 μM and an IC50 of 18.3 μM for hSR, while the IC50 of HSR-IN-1 alone is 4.7 μM. HSR-IN-1 can be used for research on central nervous system diseases[1]. |
| Target | IC50: 4.7 μM (Human Serine Racemase (HSR)) |
| Invitro | HSR-IN-1 (2-150 μM，5 分钟) 与 hSR 紧密结合，对 hSR 活性具有强效抑制作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> HSR-IN-1 相关抗体: |
| Formula | C15H16ClNO3 |
| Molar Mass | 293.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Marchesani F, et al. Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor[J]. ACS Medicinal Chemistry Letters, 2024. |