| Bioactivity | Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola. Antifungal agent 106 exhibits antifungal activity with an EC50 value of 11.8 mg/L. It affects hyphal growth by disrupting cell membrane integrity, leading to increased membrane permeability and release of intracellular electrolytes. Antifungal agent 106 can be used in research related to brown rot of stone fruits[1]. |
| Invitro | Antifungal agent 106 (3.125-50 mg/L) 对 M. fructicola 具有抑制活性，可抑制其孢子萌发和菌丝体形成，并通过诱导产生过量的内源性活性氧 (ROS) 在 M. fructicola 中引起细胞氧化损伤、酶失活和细胞膜破坏[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antifungal agent 106 相关抗体: |
| In Vivo | Antifungal agent 106 处理 (100 mg/L 和 200 mg/L，喷洒，给药时长 24 小时) 的植物体 (梨) 表现出明显较低的褐腐病发生率和较小的病斑直径，表明 Antifungal agent 106 对石果褐腐病具有抑制活性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C20H21BrFN3O2 |
| Molar Mass | 434.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zheng Y, et al. Novel mandelic acid derivatives containing piperazinyls as potential candidate fungicides against Monilinia fructicola: Design, synthesis and mechanism study. Bioorg Chem. 2024 Jul 15;151:107647. |
Antifungal agent 106
CAS: F: C20H21BrFN3O2 W: 434.30
Antifungal agent 106 (Compound Z31) is a benzoic acid derivative and a potential fungicide against Monilinia fructicola.
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This product is for research use only, not for human use. We do not sell to patients.