| Bioactivity | HSR-609 is an orally active amphoteric antiallergic agent. HSR-609 has a high affinity for histamine H1-receptor in the guinea pig cerebral cortex. HSR-609 inhibits allergic airway hyperresponsiveness to Acetylcholine. HSR-609 shows poor ability to penetrate into the CNS in mice and guinea pigs[1][2]. |
| CAS | 161522-25-4 |
| Formula | C21H21FN2O3 |
| Molar Mass | 368.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M Kakiuchi, et al. Studies on the novel antiallergic agent HSR-609: its penetration into the central nervous system in mice and guinea pigs and its selectivity for the histamine H1-receptor. Jpn J Pharmacol. 1997 Apr;73(4):291-8. [2]. K Musoh, et al. Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice. Pharmacology. 2000 Aug;61(2):70-7. |