| Bioactivity | GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism[1]. |
| CAS | 1312345-89-3 |
| Formula | C16H12N4O2S |
| Molar Mass | 324.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Beilhartz GL, et al. Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation. J Biol Chem. 2014 Jun 6;289(23):16270-7. |
GSK5750
CAS: 1312345-89-3 F: C16H12N4O2S W: 324.36
GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor. GSK5750 is bound at the RNase H a
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