| Bioactivity | HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)[1]. |
| Target | Heparanase-1 (HPSE1), exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) |
| Name | HPSE1-IN-1 |
| CAS | 2876926-29-1 |
| Formula | C30H30N2O6 |
| Molar Mass | 514.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543. |
HPSE1-IN-1
CAS: 2876926-29-1 F: C30H30N2O6 W: 514.57
HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-
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