| Bioactivity | HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC50 of 37 nM for KCNQ2[1]. | ||||||||||||
| Invitro | HN37 is a potent neuronal Kv7 activator with a subtype selectivity similar to RTG[1]. | ||||||||||||
| Name | HN37 | ||||||||||||
| CAS | 1821222-10-9 | ||||||||||||
| Formula | C20H21FN2O2 | ||||||||||||
| Molar Mass | 340.39 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64(9):5816-5837. |