| Bioactivity | (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM[1]. | ||||||||||||
| Name | (1α,1'S,4β)-Lanabecestat | ||||||||||||
| CAS | 1384082-96-5 | ||||||||||||
| Formula | C26H28N4O | ||||||||||||
| Molar Mass | 412.53 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23. |
(1α,1'S,4β)-Lanabecestat
CAS: 1384082-96-5 F: C26H28N4O W: 412.53
(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) a less active enantiomer of Lanabecestat. Lanabecestat is a potent, o
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.