| Bioactivity | HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical[1]. Storage: protect from light. | ||||||||||||
| Invitro | HKSOX-1r (5/6-mixture) (2 μM; 30 min) detects mitochondrial respiratory inhibitor-induced O2•- formation in a highly sensitive and rapid manner in HCT116, BV-2 and RAW264.7 cells[1]. | ||||||||||||
| In Vivo | HKSOX-1r (5/6-mixture) (10 μM; 20 min) detects distinct fluorescence distribution in zebrafish embryos are subjected to challenge of PMA or Antimycin A[1]. | ||||||||||||
| Name | HKSOX-1r (5/6-mixture) | ||||||||||||
| Formula | C29H15F10NO14S2 | ||||||||||||
| Molar Mass | 855.54 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Hu JJ, et, al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc. 2015 Jun 3;137(21):6837-43. |