Bioactivity | HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical[1]. Storage: protect from light. |
Invitro | HKSOX-1 (10 μM) reacts with O2•- in potassium phosphate buffer at 25 °C to produce a dramatic time-dependent fluorescence increase, which is completed within 10 min, and the fluorescence intensity remains unchanged within 60 min[1].HKSOX-1 (10 μM) exhibits excellent stability toward pH changes in the range of 2.2-8.8[1]. |
Name | HKSOX-1 (5/6-mixture) |
Formula | C23H6F10O11S2 |
Molar Mass | 712.40 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Hu JJ, et, al. Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. J Am Chem Soc. 2015 Jun 3;137(21):6837-43. |