PeptideDB

3-Nitrocoumarin

CAS: 28448-04-6 F: C9H5NO4 W: 191.14

3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor.
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Bioactivity 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1].
Target PLC-γ.
Name 3-Nitrocoumarin
CAS 28448-04-6
Formula C9H5NO4
Molar Mass 191.14
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5.