Bioactivity | 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor[1]. | ||||||||||||
Target | PLC-γ. | ||||||||||||
Name | 3-Nitrocoumarin | ||||||||||||
CAS | 28448-04-6 | ||||||||||||
Formula | C9H5NO4 | ||||||||||||
Molar Mass | 191.14 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5. |