| Bioactivity | HIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection[1]. |
| Invitro | HIV-1 inhibitor-54 (compound 4c) 对 HIV-1 突变体 E138K、K103 N、Y188L、Y181C、F227L+V106A 和 L100I 表现出较强的抗逆转录酶活性，其 EC50 值分别为 0.080 , 0.52, 0.67, 0.84, 2.7 和 3.3 μM[1]。HIV-1 inhibitor-54 抑制野生型 HIV-1 逆转录的活性，IC50 值为 12 μM[1]。 |
| Name | HIV-1 inhibitor-54 |
| CAS | 2771211-71-1 |
| Formula | C27H30N6O4S |
| Molar Mass | 534.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ming W, et al. Hybrids of delavirdine and piperdin-4-yl-aminopyrimidines (DPAPYs) as potent HIV-1 NNRTIs: Design, synthesis and biological activities. Eur J Med Chem. 2023 Feb 15;248:115114. |
HIV-1 inhibitor-54
CAS: 2771211-71-1 F: C27H30N6O4S W: 534.63
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1
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This product is for research use only, not for human use. We do not sell to patients.