| Bioactivity | HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC50 > 221 μM) and a favorable in vitro microsomal stability[1]. |
| Name | HIV-1 inhibitor-23 |
| CAS | 2554622-28-3 |
| Formula | C30H26N6O4S |
| Molar Mass | 566.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Han S, et al. Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem. 2020;185:111874. |
HIV-1 inhibitor-23
CAS: 2554622-28-3 F: C30H26N6O4S W: 566.63
HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC50s of
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This product is for research use only, not for human use. We do not sell to patients.